Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | J. HurtsJalen Hurts | K. PickettKenny Pickett | |
| Running Back | S. BarkleySaquon Barkley | K. GainwellKenneth Gainwell | |
| Wide Receiver | A. BrownA.J. Brown | D. SmithDeVonta Smith | |
| Tight End | D. GoedertDallas Goedert | C. UzomahC.J. Uzomah | |
| Left Tackle | J. MailataJordan Mailata | M. BectonMekhi Becton | |
| Left Guard | L. DickersonLandon Dickerson | M. HennessyMatt Hennessy | |
| Center | C. JurgensCam Jurgens | D. McMahonDylan McMahon | — |
| Right Guard | T. SteenTyler Steen | T. KeeganTrevor Keegan | |
| Right Tackle | L. JohnsonLane Johnson | G. AyedzeGottlieb Ayedze |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | M. WilliamsMilton Williams | M. OjomoMoro Ojomo | |
| Nose Tackle | J. DavisJordan Davis | M. TuipulotuMarlon Tuipulotu | |
| Right Defensive End | J. CarterJalen Carter | T. BookerThomas Booker | — |
| Left Inside Linebacker | N. DeanNakobe Dean | — | |
| Right Inside Linebacker | D. WhiteDevin White | O. BurksOren Burks | |
| Strongside Linebacker | N. SmithNolan Smith | Z. BaunZack Baun | |
| Weakside Linebacker | B. HuffBryce Huff | J. SweatJosh Sweat | |
| Right Cornerback | D. SlayDarius Slay | I. RodgersIsaiah Rodgers | |
| Left Cornerback | Q. MitchellQuinyon Mitchell | J. BradberryJames Bradberry | |
| Strong Safety | C. Gardner-JohnsonChauncey Gardner-Johnson | T. McCollumTristin McCollum | — |
| Free Safety | R. BlankenshipReed Blankenship | C. DeJeanCooper DeJean |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | B. MannBraden Mann | — | — |
| Kicker | J. ElliottJake Elliott | — | — |
| Long Snapper | R. LovatoRick Lovato | — | — |
| Holder | B. MannBraden Mann | — | — |
| Punt Returner | B. CoveyBritain Covey | A. SmithAinias Smith | — |
| Kick Returner | B. CoveyBritain Covey | — | — |