| Date | OPP | Time | TV | Venue | Buy Tickets |
|---|---|---|---|---|---|
| Aug 30, 2025 | vs | — | Saluki Stadium | ||
| Sep 6, 2025 | @ | — | Ross-Ade Stadium | ||
| Sep 13, 2025 | @ | — | Hardy M. Graham Stadium | ||
| Sep 20, 2025 | @ | — | Houck Stadium | — | |
| Oct 4, 2025 | vs | — | Saluki Stadium | ||
| Oct 11, 2025 | @ | — | Gate City Bank Field at the Fargodome | ||
| Oct 18, 2025 | vs | — | Saluki Stadium | ||
| Oct 25, 2025 | vs | — | Saluki Stadium | ||
| Nov 1, 2025 | @ | — | Roy Stewart Stadium | ||
| Nov 8, 2025 | @ | — | Stambaugh Stadium | ||
| Nov 15, 2025 | vs | — | Saluki Stadium | ||
| Nov 22, 2025 | @ | — | Hancock Stadium |
Overall 4-8-0 • MVC 2-6-0
Southern Illinois Salukis
- Air Force Falcons
- Akron Zips
- Alabama Crimson Tide
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- Kennesaw State Owls
- Kent State Golden Flashes
- Kentucky Wildcats
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- Louisiana Ragin' Cajuns
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- Marshall Thundering Herd
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- Michigan Wolverines
- Michigan State Spartans
- Middle Tenn. Blue Raiders
- Minnesota Golden Gophers
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- Missouri Tigers
- Missouri State Bears
- NC State Wolfpack
- Navy Midshipmen
- Nebraska Cornhuskers
- Nevada Wolf Pack
- New Mexico Lobos
- New Mexico State Aggies
- North Carolina Tar Heels
- North Texas Mean Green
- Northern Illinois Huskies
- Northwestern Wildcats
- Notre Dame Fighting Irish
- Ohio Bobcats
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- Oklahoma Sooners
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- Old Dominion Monarchs
- Ole Miss Rebels
- Oregon Ducks
- Oregon State Beavers
- Penn State Nittany Lions
- Pittsburgh Panthers
- Purdue Boilermakers
- Rice Owls
- Rutgers Scarlet Knights
- SMU Mustangs
- Sam Houston Bearkats
- San Diego State Aztecs
- San Jose State Spartans
- South Alabama Jaguars
- South Carolina Gamecocks
- South Florida Bulls
- Southern Miss Golden Eagles
- Stanford Cardinal
- Syracuse Orange
- TCU Horned Frogs
- Temple Owls
- Tennessee Volunteers
- Texas Longhorns
- Texas A&M Aggies
- Texas State Bobcats
- Texas Tech Red Raiders
- Toledo Rockets
- Troy Trojans
- Tulane Green Wave
- Tulsa Golden Hurricane
- UAB Blazers
- UCF Knights
- UCLA Bruins
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- West Virginia Mountaineers
- Western Kentucky Hilltoppers
- Western Michigan Broncos
- Wisconsin Badgers
- Wyoming Cowboys
- Overall4-8-0
- MVC2-6-0
- Air Force Falcons
- Akron Zips
- Alabama Crimson Tide
- Appalachian State Mountaineers
- Arizona Wildcats
- Arizona State Sun Devils
- Arkansas Razorbacks
- Arkansas State Red Wolves
- Army West Point Black Knights
- Auburn Tigers
- BYU Cougars
- Ball State Cardinals
- Baylor Bears
- Boise State Broncos
- Boston College Eagles
- Bowling Green Falcons
- Buffalo Bulls
- California Golden Bears
- Central Michigan Chippewas
- Charlotte 49ers
- Cincinnati Bearcats
- Clemson Tigers
- Coastal Carolina Chanticleers
- Colorado Buffaloes
- Colorado State Rams
- Connecticut Huskies
- Delaware Fightin' Blue Hens
- Duke Blue Devils
- East Carolina Pirates
- Eastern Michigan Eagles
- FIU Panthers
- Florida Gators
- Florida Atlantic Owls
- Florida State Seminoles
- Fresno State Bulldogs
- Georgia Bulldogs
- Georgia Southern Eagles
- Georgia State Panthers
- Georgia Tech Yellow Jackets
- Hawaii Rainbow Warriors
- Houston Cougars
- Illinois Fighting Illini
- Indiana Hoosiers
- Iowa Hawkeyes
- Iowa State Cyclones
- Jacksonville State Gamecocks
- James Madison Dukes
- Kansas Jayhawks
- Kansas State Wildcats
- Kennesaw State Owls
- Kent State Golden Flashes
- Kentucky Wildcats
- LSU Tigers
- Liberty Flames
- Louisiana Ragin' Cajuns
- Louisiana Tech Bulldogs
- Louisiana-Monroe Warhawks
- Louisville Cardinals
- Marshall Thundering Herd
- Maryland Terrapins
- Massachusetts Minutemen
- Memphis Tigers
- Miami (FL) Hurricanes
- Miami (OH) RedHawks
- Michigan Wolverines
- Michigan State Spartans
- Middle Tenn. Blue Raiders
- Minnesota Golden Gophers
- Mississippi State Bulldogs
- Missouri Tigers
- Missouri State Bears
- NC State Wolfpack
- Navy Midshipmen
- Nebraska Cornhuskers
- Nevada Wolf Pack
- New Mexico Lobos
- New Mexico State Aggies
- North Carolina Tar Heels
- North Texas Mean Green
- Northern Illinois Huskies
- Northwestern Wildcats
- Notre Dame Fighting Irish
- Ohio Bobcats
- Ohio State Buckeyes
- Oklahoma Sooners
- Oklahoma State Cowboys
- Old Dominion Monarchs
- Ole Miss Rebels
- Oregon Ducks
- Oregon State Beavers
- Penn State Nittany Lions
- Pittsburgh Panthers
- Purdue Boilermakers
- Rice Owls
- Rutgers Scarlet Knights
- SMU Mustangs
- Sam Houston Bearkats
- San Diego State Aztecs
- San Jose State Spartans
- South Alabama Jaguars
- South Carolina Gamecocks
- South Florida Bulls
- Southern Miss Golden Eagles
- Stanford Cardinal
- Syracuse Orange
- TCU Horned Frogs
- Temple Owls
- Tennessee Volunteers
- Texas Longhorns
- Texas A&M Aggies
- Texas State Bobcats
- Texas Tech Red Raiders
- Toledo Rockets
- Troy Trojans
- Tulane Green Wave
- Tulsa Golden Hurricane
- UAB Blazers
- UCF Knights
- UCLA Bruins
- UNLV Rebels
- USC Trojans
- UTEP Miners
- UTSA Roadrunners
- Utah Utes
- Utah State Aggies
- Vanderbilt Commodores
- Virginia Cavaliers
- Virginia Tech Hokies
- Wake Forest Demon Deacons
- Washington Huskies
- Washington State Cougars
- West Virginia Mountaineers
- Western Kentucky Hilltoppers
- Western Michigan Broncos
- Wisconsin Badgers
- Wyoming Cowboys
