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Carlos Alcaraz will try to defend his 2024 Roland Garros title at the 2025 French Open, which begins on Sunday. Alcaraz defeated Jannik Sinner in Rome and was a finalist in Barcelona, so it has been a successful clay-court swing for him thus far. Sinner returned from a three-month ban by making the final in Rome, and he won the first grand slam of the year at the Australian Open. Alcaraz is the +105 favorite (risk $100 to win $105) in the 2025 French Open odds, followed by Sinner (+210) and three-time champion Novak Djokovic (+1200). The French Open men's draw begins on Sunday at 5 a.m. ET.  

With Alcaraz and Sinner sitting well ahead of every other player atop the tennis odds board, there are many longshots available. Which players should you back with your 2025 French Open bets? Before making any 2025 French Open picks for the men's singles tournament, you need to see who proven SportsLine tennis handicapper Jose Onorato is backing.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players.

Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis betting picks. He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach has helped Onorato go 168-106-8 (+107.12 units) at sportsbooks and on betting apps since 2022. He correctly called Jannik Sinner in the 2024 US Open (+320) and the 2025 Australian Open (+160). The latest FanDuel promo code, DraftKings promo code and Fanatics Sportsbook promo code can help bettors get the most bang for their buck. 

Now, Onorato has scrutinized the latest French Open 2025 odds and released his coveted best bets to win it all. He's sharing all of his picks and analysis at SportsLine.

Top 2025 French Open men's predictions

Onorato is fading Djokovic, even though he is a three-time French Open champion. Djokovic was bounced in his first match in both Monte Carlo and Madrid, leaving him without much success during this year's clay-court swing. The 38-year-old has not won a grand slam since 2023, making just one final last year (Wimbledon). 

Djokovic won the 2023 French Open before having to withdraw prior to the quarterfinals last year. His health remains a significant concern heading into a two-week tournament, as he has not showcased the ability to make a deep run of late. Onorato says "there are just too many question marks" with this version of Djokovic, so he is avoiding the 24-time grand slam champion in the French Open. See who else to back and fade here.

How to make 2025 French Open men's picks 

Onorato has a full preview with multiple best bets, including a play on several longshots going off higher than 30-1. You can only see his French Open 2025 picks and analysis at SportsLine.

Who wins the French Open 2025, and which enormous longshots could take the crown? Visit SportsLine now to see Onorato's bets for the French Open 2025, all from the renowned tennis expert with several high-profile future wins, and find out.

2025 Men's French Open odds, top contenders

See full French Open 2025 men's picks, predictions and best bets here.

Carlos Alcaraz +105
Jannik Sinner +210
Novak Djokovic +1200
Alexander Zverev +1800
Lorenzo Musetti +2000
Casper Ruud +2900
Jack Draper +3800
Holger Rune +4400
Francisco Cerundolo +5000
Arthur Fils +5500
Alejandro Davidovich Fokina +6000
Andrey Rublev +6500
Tommy Paul +7500
Taylor Fritz +8000
Stefanos Tsitsipas +8500
Joao Fonseca +9000
Hubert Hurkacz +9500
Alex de Minaur +9500
Jakub Mensik +9500
Daniil Medvedev +10000
Frances Tiafoe +11000
Tomas Machac +12000
Felix Auger-Aliassime +12000