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Syracuse
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Last Play: 2nd & 7
L. Allen rush for no gainRun for no gain
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Syracuse vs. Louisville updates: Live NCAA Football game scores, results for Saturday

The Syracuse Orange haven't won a matchup against the Louisville Cardinals since Nov. 9 of 2018, but they'll be looking to end the drought on Saturday. 'Cuse and U of L are opening their 2022 seasons against one another at 8 p.m. ET at Carrier Dome. The Orange struggled last season, ending up 5-7. Likewise, last year was nothing to brag about for U of L (6-7), either, so the squad is looking forward to a new start.

Two last-season offensive stats to keep in the back of your head while watching: 'Cuse was 31st best in the nation (top 12%) in rushing touchdowns, finishing the 2021 season with 28. But U of L was even better: they ranked 25th in the nation in rushing touchdowns, closing the year with 29 overall (top 10%). We'll see if that edge gives the Cardinals a route to victory.

Since the experts predict a loss, the Orange will need to dig deep. Perhaps they'll be able to flip the script and come out with a big victory.

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